RevoDx HPV 14 Genotyping Kit
Infection by certain types of human papillomavirus (HPV) causes squamous intraepithelial lesions and invasive cancer of the uterine cervix and anus. HPV genotyping is important for most of the major medical indications of HPV testing. For example, genotyping of HPV has been shown to be an accurate indicator of treatment failure in follow-up after treatment for cervical dysplasia. In cervical screening, HPV genotyping better identifies women at high risk of dysplasia than does a nongenotyping HPV test, and monitoring of the types that are associated with the highest risk for cancer is particularly important. The monitoring of the effect of HPV vaccination requires adequate HPV genotyping to evaluate whether vaccine HPV types disappear from the population and how the prevalence of nonvaccine types is affected.
RevoDx HPV 14 Genotyping Kit is a real-time PCR test intended for the qualitative detection and identification of nucleic acids from 14 high-risk Human Papillomavirus (HPV) DNA.
The following HPV genotypes are detected by RevoDx HPV 14 Genotyping Kit:
The RevoDx HPV 14 Genotyping Kit is to be used with BIO-RAD CFX96 Real-Time PCR Detection Systems. But the RevoDx HPV 14 Genotyping Kit may also be compatible with most real-time PCR detection systems with the channels FAM, HEX, ROX and Cy5.
- Multiple targets (14 targets in 5 tubes)
- Ready-to-use kit
- Human RNase P as an internal control
- CE-IVD marked
- Assay duration: 60 mins
- The Limit of Detection (LoD) value is 42 IU/mL
- No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.