RevoDx Sepsis Pathogen Detection Kit
Sepsis is a syndrome that is followed by organ failure due to an uncontrolled inflammatory response of the host against infection. Early diagnosis of bloodstream infections, including those caused by bacteria and fungi, is central to reducing drastic infection-related consequences, such as significant risks of morbidity and mortality. The survival rate of septic patients mainly depends on a rapid and reliable diagnosis, since in the case of severe sepsis there is an average 7.6% decrease in survival rate per hour from the onset of hypotension without effective antimicrobial treatment. Conventional method, blood culture, has some disadvantages with regard to the desired rapidity and sensitivity. Furthermore, it is influenced by various factors and can reduce the chance of a positive result. During severe infection, empirical antibiotic therapy is inappropriate in roughly one-third of cases, and this substantially increases mortality and hospital length of stay. Furthermore, delays in optimal antimicrobial therapy may drive poor health care quality as well as increase antimicrobial resistance. As Idil Biotech, we provide a solution to all the difficulties experienced in sepsis with the RevoDx Sepsis Pathogen Detection Kit.
RevoDx Sepsis Pathogen Detection Kit is a real-time PCR test intended for the qualitative detection and identification of nucleic acids from the specific pathogens of bloodstream infection. RevoDx Sepsis Pathogen Detection Kit is performed directly on whole blood samples or on blood culture samples detected as positive.
The following pathogens and drug resistance genes are detected by RevoDx Sepsis Pathogen Detection Kit:
The RevoDx Sepsis Pathogen Detection Kit is to be used with BIO-RAD CFX96 Real-Time PCR Detection Systems. But the RevoDx Sepsis Pathogen Detection Kit may also be compatible with most real-time PCR detection systems with the channels FAM, HEX, ROX and Cy5.
- Multiple targets (29 targets in 8 tubes)
- Ready-to-use kit either in tube format or 8-Well Strips format
- Whole blood samples or blood culture samples detected as positive
- Human RNase P as an internal control
- CE-IVD marked
- Assay duration: 55 mins
- The Limit of Detection (LoD) value is 200 CFU/mL
- Diagnostic specificity is ≥ 99 %
- No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.