RevoDx Sepsis Pathogen PLUS Detection Kit

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RevoDx Sepsis Pathogen PLUS Detection Kit

Sepsis is a syndrome that is followed by organ failure due to an uncontrolled inflammatory response of the host against infection. Early diagnosis of bloodstream infections, including those caused by bacteria and fungi, is central to reducing drastic infection-related consequences, such as significant risks of morbidity and mortality. The survival rate of septic patients mainly depends on a rapid and reliable diagnosis, since in the case of severe sepsis there is an average 7.6% decrease in survival rate per hour from the onset of hypotension without effective antimicrobial treatment. Conventional method, blood culture, has some disadvantages with regard to the desired rapidity and sensitivity. Furthermore, it is influenced by various factors and can reduce the chance of a positive result. During severe infection, empirical antibiotic therapy is inappropriate in roughly one-third of cases, and this substantially increases mortality and hospital length of stay. Furthermore, delays in optimal antimicrobial therapy may drive poor health care quality as well as increase antimicrobial resistance. As Idil Biotech, we provide a solution to all the difficulties experienced in sepsis with the RevoDx Sepsis Pathogen PLUS Detection Kit.

Intended Use

RevoDx Sepsis Pathogen PLUS Detection Kit is a real-time PCR test intended for the qualitative detection and identification of nucleic acids from the specific pathogens of bloodstream infection. RevoDx Sepsis Pathogen PLUS Detection Kit is performed directly on whole blood samples or on blood culture samples detected as positive.

The following pathogens and drug resistance genes are detected by RevoDx Sepsis Pathogen PLUS Detection Kit: 

Gram Negative Bacteria

  • Pseudomonas aeruginosa

  • Klebsiella pneumonia

  • Escherichia coli

  • Acinetobacter baumannii

  • Stenotrophomonas maltophilia

  • Ureaplasma Urealytıcum

  • Neisseria meningitidis

  • Haemophilus influenzae

  • Salmonella spp

Gram Positive Bacteria

  • Staphyloccocus aureus 

  • Staphyloccocus spp 

  • Enterococcus faecalis 

  • Enterococcus faecium 

  • Streptococcus pneumoniae 

  • Streptococcus agalactiae 

  • Streptococcus pyogenes 

  • Listeria monocytogenes

Fungi

  • Candida albicans

  • Candida auris

  • Candida glabrata

  • Candida krusei

  • Candida lusitaniae

  • Candida parapsilosis

  • Candida tropicalis

  • Cryptococcus neoformans/gattii

Drug Resistance Genes

  • Carbapenem resistance (blaNDM, blaKPC, blaIMP, blaOXA48, blaVIM)

  • Methicillin resistance (mecA/mecC)

  • Vancomycin resistance (vanA/vanB)

  • Colistin resistance

  • Extended Spectrum Beta-Lactamases (ESBL) Genes (CTX-M, TEM, SHV)

Features

  • Multiple targets 10 tubes
  • Ready-to-use kit in tube format
  • Human RNase P as an internal control
  • CE-IVD marked
  • Assay duration: 45 mins
  • The Limit of Detection (LoD) value is 200 CFU/mL
  • Diagnostic specificity is ≥ 99 %
  • No cross-reactivity with the potential cross-reactive markers shown using both in silico analysis and wet testing.

Ordering Information

Product Name

Package

Cat. No.

RevoDx Sepsis Pathogen PLUS Detection Kit

24 tests

IP202470-24

RevoDx Sepsis Pathogen PLUS Detection Kit

48 tests

IP202470-48

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